OEL Fastrac

Felodipine

This monograph contains both the OEL and ADE. Felodipine is a calcium channel blocker used in the management of hypertension, congestive heart failure, and angina pectoris. Felodipine is a member of the dihydropyridine class of calcium channel antagonists (calcium channel blockers). It reversibly competes with dihydropyridine binding sites, blocking voltage-dependent Ca++ currents in vascular smooth muscle. The net effect of felodipine is a decrease of peripheral vascular resistance (i.e. reduces blood pressure), with a modest increase in heart rate.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to obtain the following information:

  • The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
  • A listing of all cited references utilized in the derivation of the OEL and ADE
  • An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

  • Fully documented. 10-12 pages in length, with calculations and cited references.
  • Save time! Unsurpassed delivery with instant download.
  • Save money. Similar documents cost 5-12 times as much.
  • Stay current. Automatic notification of revisions.

How to order

To order an OEL monograph for this compound, just click the "Add to Cart" button.

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Felodipine

CAS number:
72509-76-3
Brand name:
Plendil
Cost:
$595 USD

OEL Fastrac is an innovative way to obtain occupational exposure limit monographs for active pharmaceutical ingredients. It's super convenient and affordable, and the quality is outstanding.
  • K. Tarwater
  • EHS Manager
  • Catalent Pharma Solutions
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.
  • K. Rosenthal
  • Director of Manufacturing
  • Pharmatek Laboratories