Please note, this OEL/ADE monograph also applies to mephedrone (CAS RN 1189805-46-6) and 2-methylmethcathinone hydrochloride (CAS RN 1246815-51-9). 3-Methylmethcathinone (3-MMC, also known as metaphedrone) is a synthetic cathinone and has become one of the most popular recreational drugs worldwide to replace mephedrone (4-methylmethcathinone or 4-MMC). No evidence has been found that 3-MMC has been therapeutically used. 3-Methylmethcathionine (3-MMC) is legally controlled in many countries but is still easily available for purchase from websites and is frequently found in recreational-drug settings. Cathinone is a naturally occurring β-ketone analog of amphetamine found in the leaves of the “khat” plant (Catha edulis) consumed recreationally in the Arabian Peninsula and northeast Africa. Methcathinone is sold as “bath salts” and labeled “not for human consumption”. Bupropion is the only cathinone derivative used medically in the US and Europe. Chemically, synthetic cathinones are analogues of the natural cathinone, which in turn is closely related to amphetamines, with the addition of a ketone group at the β- position of the amino alkyl chain, which is attached to the phenyl ring. The effects of 3-MMC are commonly regarded as extremely stimulating and energetic. It is sometimes used during activities such as running, climbing and dancing.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.


CAS Registry Number:
3-MMC, metaphedrone
$679 USD


Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:

  • The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
  • A listing of all cited references utilized in the derivation of the OEL and ADE
  • An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

  • Fully documented. Over 20 pages in length, with calculations and cited references.
  • Save time! Unsurpassed delivery with instant download.
  • Save money. Similar documents cost 5-12 times as much.
  • Stay current. Automatic notification of revisions.

How to order

To order an OEL/ADE monograph for 3-Methylmethcathinone, just click the ADD TO CART button.


If you're wondering about HBEL, we have something for you.

Search OEL Fastrac

Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.

Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.
  • K. Rosenthal
  • Director of Manufacturing