Adenosine is indicated for the treatment of periodic episodes of irregular heart rate and as a stress agent, during imaging procedures, to evaluate heart function and blood flow. Adenosine slows conduction of electric impulses through a portion of the heart and can restore normal sinus rhythm in patients with intermittent irregular heart beats. Adenosine, also, causes vessels to become larger, which increases blood flow to and in the heart. Adenosine is thought to exert this pharmacological effect through activation of purine receptors (cell-surface A1 and A2 adenosine receptors).
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL monograph for this compound, just click the ADD TO CART button.
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Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.