Ammonium chloride is indicated for use in the treatment of low chloride levels in the blood, to treat metabolic alkalosis, and as an expectorant in cough syrups. Other indicated uses are as a flavor enhancer, dough strengthener, leavening agent, and as an acidifying agent. Ammonium chloride increases acidity by increasing the amount of hydrogen ion concentrations. This increase in ionization also reduces renal tubular reabsorption, allowing for increased urinary excretion. When used as an expectorant, ammonium chloride irritates the bronchial mucosa causing the production of excess respiratory tract fluid making it easier to generate a productive cough.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL/ADE monograph for Ammonium Chloride, just click the ADD TO CART button.
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Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.