OEL Fastrac Catalog

The reported CAS numbers are 8007-93-0 for belladonna extract, however, this OEL/ADE monograph also applies to 510-25-8/5878-33-1 (total alkaloids). Belladonna is a substance of unknown or variable composition, complex reaction products, or biological materials (UVCB). It consists of the dried leaf or dried leaf and flower, and occasionally fruit-bearing tops of Atropa belladonna. It contains not less than 0.30% of total alkaloids. The alkaloids consist mainly of hyoscyamine with smaller amounts of scopolamine (hyoscine).

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

Please note: Due to the complexity and amount of studies regarding this compound—a Natural Health Product—increased cost is charged.

Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:

• The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
• A listing of all cited references utilized in the derivation of the OEL and ADE
• An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

• Fully documented. Over 20 pages in length, with calculations and cited references.
• Save time! Unsurpassed delivery with instant download.
• Save money. Similar documents cost 5-12 times as much.
• Stay current. Automatic notification of revisions.

How to order

To order an OEL/ADE monograph for Belladonna, just click the ADD TO CART button.

HBEL

If you're wondering about HBEL, we have something for you.