Butylscopolamine bromide, also known as hyoscine-N-butylbromide, is a muscarinic antagonist that acts to prevent acetylcholine-stimulated contraction of smooth muscle in the gastrointestinal tract. It is used to treat abdominal cramping and pain, motion sickness, postoperative nausea and vomiting. It is also used for diagnostic procedure on eyes, mydriasis induction and cycloplegic refraction, uveitis, and iridocyclitis. Butylscopolamine bromide is also used in the treatment of delirium tremens. Butylscopolamine bromide injection (hyoscine butylbromide) is indicated for the relief of acute genitourinary or gastrointestinal spasm (renal or biliary colic), or to produce smooth muscle relaxation prior to radiological procedures such as pyelography or other diagnostic procedures where spasm may be a problem (gastroduodenal endoscopy).
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Butylscopolamine Bromide, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.