Camphor, also known as bornan-2-one, is a bicyclic monoterpene ketone found widely in plants. Camphor is a constituent of a variety of foods. Typical sources are herbs, such as basil, coriander, marjoram, rosemary and sage. Both enantiomers are naturally occurring. The essential oil from the camphor tree (Cinnamomum camphora) contains up to 84% dcamphor. Essential oils from herbs are characterized by typical ratios of the enantiomers. For example, a 72-75% excess of the l-camphor enantiomer is characteristic of coriander oil (Coriandrum sativum L.), whereas, an excess of the d-camphor enantiomer characterizes the essential oils of sage and basil. As a pharmaceutical ingredient, camphor oil has anti-inflammatory and analgesic properties and is used for its aromatic properties, as an insect repellant, in embalming fluids, and in various topical skin preparations. Additionally, camphor taken internally in small amounts (toxic in large doses) acts as a carminative, a reflex expectorant, and reflex stimulant of the heart, circulation and respiration. Camphor has also been used as a sedative and nervous system depressant in convulsions, hysteria, epilepsy, and chorea.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Camphor, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.