Caprolactam is a natural component identified in Vitis vinifera, Fagopyrum esculentum, and Nicotiana tabacum, supported by available data. It is the cyclic amide of caproic acid and serves as a key ingredient in the fabrication of synthetic polyamide fibers. The primary application of caprolactam lies in serving as an intermediate in the production of nylon 6 polymers, known for their versatile applications including textiles, carpets, industrial yarns, engineering plastics utilized in both industrial and medical contexts, and various consumer goods like cosmetics, diapers, and 3D-printing filaments. Some residual caprolactam may be present in products crafted from nylon 6. Additionally, caprolactam finds utility as a plasticizer and is integrated into the formulation of paints, coatings, adhesive products like glue sticks, and other adhesives. Furthermore, caprolactam may also contribute as a component in the production of specific food packaging materials and as a food flavoring agent. Caprolactam is used in the manufacture of synthetic fibers.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.


CAS Registry Number:
$679 USD


Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:

  • The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
  • A listing of all cited references utilized in the derivation of the OEL and ADE
  • An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

  • Fully documented. Over 20 pages in length, with calculations and cited references.
  • Save time! Unsurpassed delivery with instant download.
  • Save money. Similar documents cost 5-12 times as much.
  • Stay current. Automatic notification of revisions.

How to order

To order an OEL/ADE monograph for Caprolactam, just click the ADD TO CART button.


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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.
  • K. Rosenthal
  • Director of Manufacturing