Please note, this OEL/ADE monograph also applies to carbidopa monohydrate (CAS RN 38821-49-7). Carbidopa is indicated for the treatment of Parkinson’s disease. Carbidopa inhibits the decarboxylation of peripheral levodopa, making more levodopa available for transport across the blood-brain barrier. Carbidopa inhibits the decarboxylation of peripheral levodopa, making more levodopa available for transport across the blood-brain barrier. Carbidopa does not cross the bloodbrain barrier; thus, it prevents the metabolism of levodopa peripherally, but does not have an effect on the generation of dopamine in the brain.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Carbidopa, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.