Chlorobutanol (also known as chlorbutol, trichloro-2-methyl-2-propanol, acetochlorone, acetone chloroform, chloretone, chlortran and chloreton), is an alcohol-based preservative with no surfactant activity. Chlorobutanol has been widely used as sedative-hypnotic agent used for procedural sedation, particularly in the pediatric population, and to treat anxiety, insomnia, and alcohol withdrawal syndrome. It is used as a preservative in ophthalmic, parenteral, and optic preparations, due to its antibacterial and antifungal properties. Additionally, it has been used in preparations for inflammatory and painful conditions of the ear and oropharynx.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Chlorobutanol, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.