Clavulanate potassium has little therapeutic activity itself. Instead, it is used in combination with other antibiotics to increase their effectiveness. Amoxicillin plus clavulanate potassium (Augmentin®) is one such combination used to treat lower respiratory tract infections, ear infections, sinus infections, skin infections and urinary tract infections and is used in veterinary medicine. Clavulanate potassium is a semi-synthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanate potassium contains a beta-lactam ring and binds strongly to betalactamase at or near its active site. This protects other beta-lactam antibiotics from betalactamase catalysis.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Clavulanate Potassium, just click the ADD TO CART button.
If you're wondering about HBEL, we have something for you.
Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.