Please note, this OEL/ADE monograph also applies to clonidine hydrochloride (CAS RN 4205-91-8). This monograph contains both the OEL and ADE. Clonidine is a sympatholytic medication used to treat medical conditions, such as high blood pressure, some pain conditions, ADHD and anxiety or panic disorder. Clonidine treats high blood pressure by stimulating the alpha-2 receptors in the brain, which decreases cardiac output and peripheral vascular resistance, thus lowering blood pressure. It has also been proposed that the antihypertensive effect of clonidine is due to agonism on the imidazoline receptor, which mediates the sympatho-inhibitory actions of imidazolines to lower blood pressure.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Clonidine, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.