Please note, this OEL/ADE monograph also applies to methylcyclopentane (CAS RN 96-37-7), 1,2-Epoxycyclopentane (cyclopentene oxide) (CAS RN 285-67-6), and cyclopentane carboxylic acid (CAS RN 3400-45-1). Cyclopentane, the parent of the class of cyclopentanes, is a cycloalkane that consists of five carbons each bonded with two hydrogens above and below the plane. It has a role as a nonpolar solvent. It is a member of cyclopentanes, a cycloalkane and a volatile organic compound. Cyclopentane is used chiefly as a laboratory reagent. It is found in petroleum ether and other commercial solvents that are used as fuel, in fat and wax extraction, in paints, and in the shoe industry. It is also used as a solvent for cellulose ethers, in motor fuel, and as an azeotropic distillation agent. Industrially, cyclopentane is used for cracking aromatics. Commercially, it is used to produce a variety of chemicals used as analgesics, sedatives, hypnotics, antitumor drugs, central nervous system depressants, prostaglandins, and insecticides.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
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