Please note, this OEL/ADE monograph also applies to alternate CAS RN 5996-10-1 and dextrose anhydrous (CAS RN 50-99-7). Dextrose is used to treat very low blood sugar (hypoglycemia), most often in people with diabetes mellitus. Dextrose is given by injection to treat insulin shock (low blood sugar caused by using insulin and then not eating a meal or eating enough food afterward). This medicine works by quickly increasing the amount of glucose in the blood. Dextrose (D- glucose) is a primary source of energy for living organisms. It is naturally occurring. It is metabolized via the Krebs (also known as citric acid cycle or tricarboxylic acid cycle (TCA)) via oxidative decarboxylation, providing energy in the form of ATP.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
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