OEL Fastrac Catalog

Please note, this OEL/ADE monograph also applies to 3,4-Dichloroaniline (CAS RN 95-76-1), 2,6-Dichloroaniline (CAS RN 608-31-1), 2,5-Dichloroaniline (CAS RN 95-82-9), 2,4-Dichloroaniline (CAS RN 554-00-7), 2,3-Dichloroaniline (CAS RN 608-27-5), and 3,5-Dichloroaniline (CAS RN 626-43-7). Dichloroanilines (DCAs) are used as intermediates in the production of pesticides, drugs, dyes (including azo dyes), and antimicrobials. Limited hazard information is available for the individual DCA isomers. The majority of available data are for the 3,4-DCA and 2,3-DCA isomers and some isomers have little or no data. Due to the functional group structural similarity including two chlorine and one amino group attached directly to the benzene ring, similarity of the physicochemical properties including melting point, boiling point, and log Kow, and similarity in most toxicologically relevant human health effects, where available, including acute toxicity, repeat-dose toxicity, and genotoxicity.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:

• The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
• A listing of all cited references utilized in the derivation of the OEL and ADE
• An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

• Fully documented. Over 20 pages in length, with calculations and cited references.
• Save time! Unsurpassed delivery with instant download.
• Save money. Similar documents cost 5-12 times as much.
• Stay current. Automatic notification of revisions.

How to order

To order an OEL/ADE monograph for Dichloroaniline, just click the ADD TO CART button.

HBEL

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