Durapatite, also known as hydroxyapatite, hydroxylapatite and calcium phosphate tribasic, is the major mineral component of bones and teeth and it has been therapeutically used as a prosthetic aid and as a calcium supplement in the prevention and treatment of osteoporosis. Hydroxyapatite is also used in cosmetics. It is added to cornstarch-based baby powders and acts as an emollient to “help moisturize and soften the skin”. Its synthetic form nanohydroxyapatite, is used in different commercial oral care products treatment, such as toothpastes and mouthwashes to treat dental sensitivity and to promote enamel remineralisation.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Durapatite, just click the ADD TO CART button.
If you're wondering about HBEL, we have something for you.
Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.