Please note, this OEL/ADE monograph also applies to Ergonovine maleate (CAS RN 129-51-1), ergonovine hydrochloride (CAS RN 6034-13-5), ergonovine phosphate (CAS RN N.A.), and ergonovine tartrate (CAS RN 129-50-0). Ergonovine (also known as ergometrine) is a naturally occurring alkaloid found in ergot (Claviceps purpurea) and in Jacquemontia tamnifolia, Acremonium, and other organisms. In human medicine, ergometrine is used as a maleate salt to prevent or treat postpartum and postabortion hemorrhage. Ergometrine is used in the active management of the third stage of labor. It is used in veterinary medicine in the control of postpartum uterine hemorrhage, removal of fluid from atonic uteri, to prevent prolapsed uteri, and judiciously in terms of timing to aid in suturing the uterus after cesarean section or in replacing an everted uterus.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Ergonovine, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.