Affygility Solutions has developed and made available for online purchase, an occupational exposure limit for Escitalopram Oxalate (Escitalopram). This 8-page document was created by occupational health professionals with advanced degrees and decades of industry experience. Escitalopram is a selective serotonin reuptake inhibitor; it is the S(+)-enantiomer of citalopram and is used in the treatment of depression. The mechanism of antidepressant action of Escitalopram is presumed to be linked to potentiation of serotonergic activity in the central nervous system resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT) (2). 5-HT has long been recognized as an effector on various types of smooth muscle and an agent that enhances platelet aggregation and as a neuorotransmitter in the central nervous system.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL monograph for this compound, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.