OEL Fastrac New and updated OEL Fastrac monographs from Affygility Solutions https://affygility.com/oel/ en Copyright © Affygility Solutions oelfastrac@affygility.com https://affygility.com/apple-touch-icon-oel-fastrac.png OEL Fastrac https://affygility.com/oel/ Boldo Extract https://affygility.com/oel/boldo-extract.html Thu, 16 Apr 2026 09:59:06 -0600 oel-fastrac-79459370 Affygility Solutions Boldo leaf (Boldo folium, from Peumus boldus Mol.) is used in traditional herbal medicine for symptomatic relief of dyspepsia and mild spasmodic disorders of the gastrointestinal (GI) tract and to stimulate digestion. Boldo leaf is also used as a diuretic, for hepatobiliary disorders, and for GI disorders such as constipation. Boldo extract is used as a flavoring for alcoholic beverages (3, 7). Boldo leaf extract is also used for allergy testing. Boldo leaf is also used as a diuretic, for hepatobiliary disorders, and for GI disorders such as constipation. Boldo extract is used as a flavoring for alcoholic beverages (3, 7). Boldo leaf extract is also used for allergy testing. The bark of the Peumus boldus tree, although harvested on a much smaller scale, is the main industrial source of boldine.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value, the acceptable surface limit (ASL), and the Permitted Daily Exposure (PDE) value.

The OEL Fastrac monograph for Boldo Extract is available for purchase for $1,399 USD.

]]> Insulin Aspart https://affygility.com/oel/insulin-aspart.html Fri, 03 Apr 2026 08:27:23 -0600 oel-fastrac-79449928 Affygility Solutions Insulin aspart is a recombinant human insulin analog with rapid-acting blood glucoselowering activity produced by recombinant deoxyribonucleic acid (DNA) technology with an altered pharmacokinetic profile compared to endogenous human insulin. Structurally, it is a two-chain peptide comprising 51 amino acids, with the A-chain containing 21 amino acids and the B-chain containing 30 amino acids. It is identical to human insulin in primary structure except for a substitution of proline by aspartic acid at position B28. Clinically, insulin aspart is indicated for glycemic control in patients with diabetes mellitus type 1 (DMT1) and diabetes mellitus type 2 (DMT2), in both adult and pediatric populations.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value and the Permitted Daily Exposure (PDE) value.

The OEL Fastrac monograph for Insulin Aspart is available for purchase for $989 USD.

]]> Voglibose https://affygility.com/oel/voglibose.html Fri, 03 Apr 2026 08:27:21 -0600 oel-fastrac-79449927 Affygility Solutions Voglibose is a valiolamine derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. It is indicated for lowering postprandial blood glucose levels in people with diabetes, alone or in combination with oral hypoglycemic agents or insulin therapy. It is also indicated for suppression of the onset of type 2 diabetes in patients with impaired glucose tolerance.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value and the Permitted Daily Exposure (PDE) value.

The OEL Fastrac monograph for Voglibose is available for purchase for $989 USD.

]]> Ilunocitinib https://affygility.com/oel/ilunocitinib.html Thu, 26 Mar 2026 15:08:13 -0600 oel-fastrac-79449152 Affygility Solutions Ilunocitinib is an immunomodulator and member of the Janus kinase (JAK) inhibitor (JAKi) class used in veterinary medicine for the treatment and control of symptoms of allergic skin disease conditions, such as pruritus associated with allergic dermatitis and atopic dermatitis in dogs.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Ilunocitinib is available for purchase for $989 USD.

]]> Catalase https://affygility.com/oel/catalase.html Thu, 26 Mar 2026 15:08:11 -0600 oel-fastrac-79449151 Affygility Solutions Catalase is an antioxidant enzyme obtained from many biological sources including animal liver (hepatocatalase) and certain bacteria and fungi. It has been applied to wounds and skin ulcers and has also been used in the treatment of vitiligo. It has sometimes been included in preparations for contact lens care to neutralize H2O2. Catalase has various industrial applications. In the food industry, it is used in combination with other enzymes in the preservation of foodstuffs and in the manufacture of beverages and certain food items. Commercial catalases are also used to break down H2O2 in wastewater. Catalase can be used as a dietary supplement indicated for endogenous antioxidant support. It aids in protecting cells against oxidative stress. Catalase contributes to the maintenance of redox homeostasis, acting on mitochondria and peroxisomes. Catalase can be used as an adjuvant in protocols and formulations aimed at aging and conditions associated with oxidative stress (indirect use). Catalase aids in the antioxidant protection of the hair follicle, contributing to the reduction of oxidative stress associated with the progressive loss of hair pigmentation, and it contributes to the maintenance of a physiologically balanced follicular environment, promoting the integrity of the structures involved in hair growth.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Catalase is available for purchase for $989 USD.

]]> Benzyl Alcohol https://affygility.com/oel/benzyl-alcohol.html Thu, 26 Mar 2026 15:08:08 -0600 oel-fastrac-79449150 Affygility Solutions Benzyl alcohol, also known as benzenemethanol and hydroxytoluene, is an aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent (1). Benzyl alcohol is reported to function as a fragrance, pH adjuster, preservative, solvent, antioxidant, viscosity decreasing agents, and external analgesics. It is also used as a food additive, cosmetic ingredient, chemical in photographic developing systems, disinfectant, and antibacterial agent in a variety of pharmaceutical formulations intended for intravenous (IV) administration. Benzyl alcohol is a Food and Drug Administration (FDA)-approved diluent in color additive mixtures for external drug use As an active ingredient, benzyl alcohol lotion, 5%, is used as a prescription medication for the treatment of head lice (Pediculosis capitis) (2, 3, 4). It is also used as an oral pain reliever for the temporary relief of pain caused by cold sores/fever blisters, canker sores, mouth sores, gum irritations, toothaches, minor irritation of the mouth and gum, sore mouth, and sore throat.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Benzyl Alcohol is available for purchase for $989 USD.

]]> Gabapentin Enacarbil https://affygility.com/oel/gabapentin-enacarbil.html Thu, 26 Mar 2026 15:08:06 -0600 oel-fastrac-79449149 Affygility Solutions Please note, this OEL/ADE monograph also applies to dabapentin enacarbil sodium (CAS RN 912486-72-7).Gabapentin enacarbil is a long-acting prodrug of gabapentin that is used for restless leg syndrome (RLS) and for painful postherpetic neuropathy (PHN).

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Gabapentin Enacarbil is available for purchase for $989 USD.

]]> Eplontersen https://affygility.com/oel/eplontersen.html Thu, 26 Mar 2026 15:08:04 -0600 oel-fastrac-79449148 Affygility Solutions Please note, this OEL/ADE monograph also applies to eplontersen sodium (CAS RN 2131025-75-5). Eplontersen is a transthyretin-directed antisense oligonucleotide (ASO) covalently linked to a ligand containing three N-acetyl galactosamine (GalNAc) residues to enable delivery of the ASO to hepatocytes (1, 2). Eplontersen is indicated for the treatment of polyneuropathy associated with stage 1 or stage 2 hereditary transthyretin-mediated amyloidosis (hATTR) in adults.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Eplontersen is available for purchase for $989 USD.

]]> Gadopiclenol https://affygility.com/oel/gadopiclenol.html Thu, 26 Mar 2026 15:08:01 -0600 oel-fastrac-79449147 Affygility Solutions Gadopiclenol is a gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity in the central nervous system (CNS) (including brain, spine, and associated tissues) and the body (head and neck, thorax, abdomen, pelvis, and musculoskeletal system). Gadopiclenol is available as injection solution for intravenous (IV) administration.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Gadopiclenol is available for purchase for $989 USD.

]]> Elinzanetant https://affygility.com/oel/elinzanetant.html Fri, 06 Mar 2026 13:06:10 -0700 oel-fastrac-79446566 Affygility Solutions Elinzanetant is an orally bioavailable neurokinin (NK)/tachykinin 1 receptor (NK1R) and NK3 receptor (NK3R) antagonist used for the treatment of moderate to severe vasomotor symptoms associated with menopause and caused by adjuvant endocrine therapy (AET) related to breast cancer.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Elinzanetant is available for purchase for $989 USD.

]]> Xanomeline https://affygility.com/oel/xanomeline.html Fri, 06 Mar 2026 13:06:08 -0700 oel-fastrac-79446565 Affygility Solutions Xanomeline is a muscarinic agonist used in conjunction with trospium, a muscarinic antagonist, to treat schizophrenia in adults. Please note, this OEL/ADE monograph also applies to xanomeline tartrate (CAS RN 152854-19-8) and xanomeline tartrate hydrochloride.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Xanomeline is available for purchase for $989 USD.

]]> Zinc chloride https://affygility.com/oel/zinc-chloride.html Fri, 06 Mar 2026 13:06:05 -0700 oel-fastrac-79446564 Affygility Solutions Compound description

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Zinc chloride is available for purchase for $989 USD.

]]> Aficamten https://affygility.com/oel/aficamten.html Wed, 25 Feb 2026 12:11:02 -0700 oel-fastrac-79444980 Affygility Solutions Aficamten is a second-in-class cardiac myosin inhibitor indicated for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) to improve functional capacity and symptoms.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Aficamten is available for purchase for $989 USD.

]]> Birch Triterpenes https://affygility.com/oel/birch-triterpenes.html Wed, 25 Feb 2026 12:10:57 -0700 oel-fastrac-79444979 Affygility Solutions Birch triterpenes, also known as birch bark extract (BBE) or triterpene extract (TE), is an herbal extract rich in triterpenoids. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch triterpenes are obtained from the white part of the birch tree bark, and the main species of trees used for production are Betula pendula (silver birch) and Betula pubescens (white birch) although hybrids of both species are used as well. A gel preparation of birch triterpenes (10% of birch triterpene dry extract in sunflower oil, also known as Oleogel-S10®) is indicated for the topical treatment of partialthickness wounds associated with dystrophic and junctional epidermolysis bullosa (EB) in patients 6 months old and older. This birch triterpene dry extract contains 84% to 95% triterpenes calculated as the sum of betulin, betulinic acid, erythrodiol, lupeol, and oleanolic acid.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Birch Triterpenes is available for purchase for $989 USD.

]]> Galcanezumab https://affygility.com/oel/galcanezumab.html Wed, 25 Feb 2026 12:10:54 -0700 oel-fastrac-79444978 Affygility Solutions Galcanezumab is a monoclonal antibody to the calcitonin gene-related peptide (CGRP). It is used for prevention of migraine in patients with episodic or chronic migraine headaches and for the treatment of episodic cluster headache. Galcanezumab has not been associated with serum enzyme elevations during therapy, nor has it been implicated in cases of clinically apparent drug-induced liver injury with jaundice.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Galcanezumab is available for purchase for $989 USD.

]]> Oliceridine https://affygility.com/oel/oliceridine.html Wed, 25 Feb 2026 12:10:48 -0700 oel-fastrac-79444977 Affygility Solutions Please note, this OEL/ADE monograph also applies to oliceridine hydrochloride (CAS RN 1401031-39-7) and oliceridine fumarate (CAS RN 1467617-09-9). Oliceridine, formerly known as TRV130, is a biased opioid agonist with analgesic effects. Oliceridine is indicated in adults for the management of acute pain severe enough to require intravenous (IV) opioid analgesics and for whom no acceptable alternative treatments exist. Oliceridine is a United States (US) Drug Enforcement Administration (DEA) Schedule II controlled substance. Oliceridine was available as an injection solution for IV administration.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Oliceridine is available for purchase for $989 USD.

]]> Ensartinib https://affygility.com/oel/ensartinib.html Wed, 25 Feb 2026 12:10:44 -0700 oel-fastrac-79444976 Affygility Solutions Please note, this OEL/ADE monograph also applies to Ensartinib hydrochloride (CAS RN 2137030-98-7). Ensartinib is an aminopyridazine-based small-molecule tyrosine kinase inhibitor (TKI). It is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive locally advanced non-small cell lung cancer (NSCLC) or adult patients with metastatic NSCLC who have also previously not received an ALK-inhibitor.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Ensartinib is available for purchase for $989 USD.

]]> Inavolisib https://affygility.com/oel/inavolisib.html Mon, 16 Feb 2026 19:28:07 -0700 oel-fastrac-79443869 Affygility Solutions Inavolisib is a small molecule indicated in combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, phosphatidylinositol 3-kinase (PI3K)CAmutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Inavolisib is available for purchase for $989 USD.

]]> Odevixibat https://affygility.com/oel/odevixibat.html Mon, 16 Feb 2026 19:28:04 -0700 oel-fastrac-79443868 Affygility Solutions Please note, this OEL/ADE monograph also applies to Odevixibat hydrochloride (CAS Not Available) and Odevixibat sesquihydrate (CAS RN 2409081-01-0). Odevixibat, also known as A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated in the treatment of pruritus in patients with progressive familial intrahepatic cholestasis (PFIC). It is also indicated for the treatment of cholestatic pruritus in patients 12 months of age and older with Alagille syndrome (ALGS).

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Odevixibat is available for purchase for $989 USD.

]]> Perfluorohexyloctane https://affygility.com/oel/perfluorohexyloctane.html Mon, 16 Feb 2026 19:28:01 -0700 oel-fastrac-79443867 Affygility Solutions Perfluorohexyloctane is a semifluorinated alkane. Perfluorohexyloctane has been used in the field of ophthalmology as a vitreous substitute. Perfluorohexyloctane ophthalmic formulation is indicated for the treatment of the signs and symptoms of dry eye disease. It is indicated to provide temporary tamponade during ophthalmic procedures such as retinal reattachment.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

The OEL Fastrac monograph for Perfluorohexyloctane is available for purchase for $989 USD.

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