Gallium is a rare, silvery (usually trivalent) metallic element. Gallium can be used to detect such diseases as Hodgkin’s disease, lymphomas, and interstitial lung disease. Gallium nitrate is also used as an anticancer drug for lymphomas and bones. It can reverse bone degeneration and/or hypercalcemia cancer, osteoporosis, and Paget’s syndrome. In the case of therapeutic action, gallium halts bone resorption, normalizes serum calcium levels, adds bone mass, and kills cancer cells. Some gallium drugs become acute renal toxins at 10 to 100 times the therapeutic dose. Gallium does not accumulate in tissues, nor does it cause mutations or show other signs of toxicity. In dental applications, gallium alloys are nonstaining and used in the fabrication and repair of dental prostheses. These alloys exhibit a sufficiently high solder temperature, enabling pre-soldering of the alloy without distortion of the restoration.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Gallium, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.