Gestodene is a synthetic progestogen hormonal contraceptive that is used in combination with ethinyl estradiol for oral contraception. Gestodene is also used in menopausal hormone therapy. Gestodene is a progestogen structurally related to levonorgestrel. Gestodene is reported to have few androgenic effects and to have less adverse effects on the serum lipid profile than older 19-nortestosterone derivatives. However, there is some evidence that gestodenecontaining combined oral contraceptives (OCs) are associated with a small increased risk of venous thromboembolism.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Gestodene, just click the ADD TO CART button.
If you're wondering about HBEL, we have something for you.
Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.