Iron is an essential trace element required by all forms of life. In man it is required for the synthesis of heme proteins which function in the process of oxygen transport and oxidative metabolism. They include hemoglobin, myoglobin, the cytochromes as well as catalase and peroxides. Other enzyme systems such as succinic dehydrogenase, mitochondrial nicotinamide adenine dinucleotide hydrogen (NADH)-dehydrogenase and xanthine oxidase contain nonheme iron. In other enzyme systems, such as aconitase, iron is a cofactor. Iron occurs as a natural constituent of all foods of plant and animal origin and may also be present in drinking-water. In food, iron occurs in three forms, iron oxides, inorganic and organic salts, and organic complexes such as heme iron. The chemical form of iron is important in assessing its biological availability. In addition, food may be fortified with iron salts or elemental iron. Most of the iron in the diet of people living in the United States (US) is derived from meat and grain products.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Iron Hydroxide, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.