Please note, this OEL/ADE monograph also applies to isoproterenol sulfate (CAS RN 6078-56-4) and isoproterenol hydrochloride (CAS RN 51-30-9). Isoproterenol is indicated for the treatment of multiple conditions including anesthesia for bronchospasm, asthma, heart attack, heart related shock, congestive heart failure, decreased vascular flow, heart block, blood volume related shock, and fainting. Isoproterenol hydrochloride is a potent nonselective beta-adrenergic agonist having low affinity for alpha-adrenergic receptors. Systemic effects include lowering of peripheral vascular resistance and diastolic blood pressure, direct effects on the heart, and prevention of airway constriction.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL/ADE monograph for Isoproterenol, just click the ADD TO CART button.
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Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.