Isosorbide dinitrate is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. It is indicated for the prevention of angina pectoris due to coronary disease. Isosorbide dinitrate has also been investigated in myocardial infarction. Isosorbide dinitrate is also indicated intravenously (IV) for the treatment of unresponsive left ventricular failure, secondary to acute myocardial infarction, unresponsive left ventricular failure of various etiologies and severe or unstable angina pectoris. It is also used to facilitate or prolong balloon inflation and to prevent or relieve coronary spasm during percutaneous transluminal coronary angioplasty.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API).
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL monograph for Isosorbide dinitrate, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.