Ivy leaf extract taken from hedera helix L. folium is used as an expectorant in cases of productive cough. It has been used to treat chronic asthma for many years. Ivy leaf has been used for centuries to treat diverse diseases. It has been evaluated for its usefulness in treating upper respiratory infections. Information on the mechanism of action of the all the components of ivy leaf could not be located. Saponines are considered the primary component responsible for the broncholytic and secretolytic efficacy of ivy leaves. Specific saponines prevent internalization of B2- adenergic receptors on the surface of bronchial smooth muscle cells and alveolar type II cells.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL monograph for this compound, just click the ADD TO CART button.
Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.