Sodium lauryl ether sulfate (SLES), commonly referred to as sodium laureth sulfate, is a widely used surfactant in household detergents, personal care products, and cosmetics. Alkyl ether sulphates (AES) are anionic surfactants which are used as foaming agents. Among AES, SLES is known for its exceptional performance and cost-effectiveness. Distinguished from sodium lauryl sulfate (SLS) or sodium dodecyl sulfate (SDS), SLES is produced from lauryl alcohol through ethoxylation. It is particularly favored for its efficient foaming and cleaning properties, widely found in shampoos, body washes, toothpaste, and various cleaning solutions. Despite being anionic surfactants, the ethoxylation process renders SLES milder in comparison to SLS, providing a gentler cleansing experience in personal care formulations. Sodium lauryl ether sulfate is considered a mixture that varies in composition and physical-chemical properties, mainly depending on the length of the hydrocarbon chain. Information regarding AES and SLS will be used for the purpose of this monograph when necessary.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.