Please note, this OEL/ADE monograph also applies to the additional CAS RN 333963-40-9). Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 and a chloride channel 2 (ClC-2) activator with laxative activity. It is used for the treatment of chronic idiopathic constipation, opioid-induced constipation in patients with chronic non-cancer pain, and treatment of irritable bowel syndrome with constipation (IBS-C) in female adult patients.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Lubiprostone, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.