Methamphetamine HCl is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) and obesity. Methamphetamine HCl is a sympathomimetic amine with central nervous system (CNS) stimulatory activity. The peripheral actions include elevation of systolic and diastolic blood pressures and weak bronchodilator and respiratory stimulant activity. In treating obesity, it has not been established if the action is primarily one of appetite suppression, other central nervous system actions, or if metabolic effects may be involved. The mechanism of action involved in producing behavioral changes in children with attention deficit hyperactivity disorder is unknown.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
The OEL/ADE monograph for Methamphetamine HCl is under development.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.