Please note, this OEL/ADE monograph also applies to morphine sulfate (CAS RN 64-31-3), morphine hydrochloride trihydrate (CAS RN 6055-06-7), and morphine tartrate (CAS RN 302-31-8). Morphine sulfate is an opioid analgesic indicated for treating many diverse types of pain. Morphine is also indicated for many various conditions. Morphine sulfate is a pure opioid agonist, selective to the mu receptor, with primary actions in the brain through transitory stimulation prior to depression. In the CNS, it promotes analgesia and respiratory depression by decreasing brain stem respiratory centers response to carbon dioxide tension and electrical stimulation. It also decreases gastric, biliary and pancreatic secretion, induces peripheral vasodilation and promotes opioid-induced hypotension due to histamine release.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL/ADE monograph for Morphine, just click the ADD TO CART button.
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Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.