Morpholine

Please note, this OEL/ADE monograph also applies to Morpholine hydrochloride (CAS RN 10024-89-2), Morpholine nitrite (CAS RN 62076-93-1), Morpholine, sulfite (1 to 1) (CAS RN 76088-23-8), Morpholine sulfamate (CAS RN 52636-67-6), Morpholine, phosphate (3 to 1) (CAS RN 34668-73-0), Morpholine salicylate (CAS RN 147-90-0), Morpholinium palmitate (CAS RN 69228-44-0), and Morpholine oleic acid salt (CAS RN 1095-66-5). Morpholine an organic heteromonocyclic compound. Morpholine has a wide range of applications, including use as a corrosion inhibitor, optical bleacher, food additive, chemical intermediate, antioxidant, wax and polish emulsifier, corrosion inhibitor, solvent for resins, waxes, casein, and dyes, boiler additive, intermediate in the production of rubber accelerators, and intermediate in the production of optical brighteners for detergent. Morpholine also is used as a polymerization inhibitor, a catalyst for certain chemical reactions, a gelling agent in the preparation of catalysts, a separating agent for various purification procedures, to stabilize thermally cellulose materials, and as a preservative for book paper.

Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

Morpholine

CAS Registry Number:
110-91-8
Synonyms:
diethylenimide oxide, diethylene oximide
Trade name:
Drewamine®
Cost:
$679 USD

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Why do you need this OEL Fastrac monograph?

OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:

  • The numerical OEL and control band assignment needed to determine the level of required engineering controls and personal protective equipment
  • A listing of all cited references utilized in the derivation of the OEL and ADE
  • An expert review and discussion with respect to the critical endpoints of concern, the rationale for the choice of endpoints, and dose that is to be used in the derivation of the ADE (PDE), as required by the EMA's Guideline on setting health-based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities

Benefits of OEL Fastrac monographs

  • Fully documented. 10-12 pages in length, with calculations and cited references.
  • Save time! Unsurpassed delivery with instant download.
  • Save money. Similar documents cost 5-12 times as much.
  • Stay current. Automatic notification of revisions.

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To order an OEL/ADE monograph for Morpholine, just click the ADD TO CART button.

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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.
  • K. Rosenthal
  • Director of Manufacturing