Nalbuphine hydrochloride is an injectable analgesic (pain killer) used to treat pain when an opiate analgesic is required and other treatments are inadequate. Nalbuphine hydrochloride is a synthetic opioid agonist-antagonist analgesic (pain killer) for parenteral use, related chemically to the opioid oxymorphone, and to the opioid antagonist naloxone. Nalbuphine has an analgesic (agonist action) potency equivalent to that of morphine on a milligram for milligram basis. Receptor studies show that nalbuphine binds to mu, kappa, and delta receptors, but not to sigma receptors.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL monograph for this compound, just click the ADD TO CART button.
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Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.