Please note, this OEL/ADE monograph also applies to the alternate CAS RN 83834-59-7. Octinoxate (also known as octylmethoxycinnamate, 2-ethylhexyl 4-methoxycinnamate, and ethylhexyl methoxycinnamate) is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize deoxyribonucleic acid (DNA) photodamage. It was originally developed as an organic ultraviolet (UV)-B filter that absorbs UV-B rays from the sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and decrease the risk of percutaneous absorption. Its use in pharmaceutical and cosmetic formulations and is approved by the Food and Drug Administration (FDA).
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Octinoxate, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.