Please note, this OEL/ADE monograph also applies to pamidronate disodium anhydrous (CAS RN 57248-88-1), pamidronate monosodium (CAS RN 89131-02-2), and pamidronate disodium (CAS RN 109552-15-0). Pamidronic acid is a second-generation, nitrogen-containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second-generation bisphosphonates are less common than third-generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid. Pamidronic acid, administered as pamidronate disodium, is indicated to treat moderate to severe hypercalcemia of malignancy, moderate to severe Paget's disease of the bone, osteolytic bone metastases of breast cancer, and osteolytic lesions of multiple myeloma.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Pamidronic Acid, just click the ADD TO CART button.
If you're wondering about HBEL, we have something for you.
Not the compound you were looking for? You can search the OEL Fastrac catalog to find more available compounds.
Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.