Please note, this OEL/ADE monograph also applies to alternate CAS RN 6735-59-7, pralidoxime chloride (CAS RN 51-15-0), pralidoxime iodide (CAS RN 94-63-3), pralidoxime bromide (CAS RN 14018-51-0), and pralidoxime methyl sulfate (CAS RN 1200-55-1). Pralidoxime is a cholinesterase reactivator. It is used in combination with atropine for the treatment of poisoning by susceptible organophosphorus nerve agents having anticholinesterase activity in adults. It is also used in the control of overdosage by anticholinesterase drugs used in the treatment of myasthenia gravis.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Pralidoxime, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.