Please note, this OEL/ADE monograph also applies to sennoside A (CAS RN 81-27-6), senoside B (CAS RN 128-57-4), senoside B calcium salt (52730-37-7), Sennosides A and B (CAS RN 62211-03-4), Sennoside A calcium salt (CAS RN 52730-36-6), Sennoside B calcium salt (CAS RN 52730-37-7), and Sennoside G (CAS RN 66575-30-2). Sennoside is an anthranoid chemically described as an anthraquinone glycoside found in the senna plant (Senna alexandrina, also known as Cassia angustifolia), and usually referred to the diastereoisomeric mixture of sennosides A and B. Anthranoid derivatives are used all over the world as a treatment for constipation.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), as well as PIC/S and ANVISA requirements, and to obtain the following information:
To order an OEL/ADE monograph for Sennoside, just click the ADD TO CART button.
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Affygility Solutions’ OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.