Zinc acetate is used as maintenance therapy to inhibit copper absorption from the intestine in patients with Wilson’s disease and in treatment of pregnant/pre-symptomatic patients. It is also used as an indirect food additive for use as a component of adhesives, as a source of zinc in nutritional supplements, and in over-the-counter medications including skin protectants. Zinc, the active component of zinc acetate, induces the production of copper binding protein in intestinal cells. The bound copper is eliminated in the feces and not absorbed systemically.
Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.
OEL Fastrac monographs are a cost-effective and convenient way to meet the requirements for PDEs (ADEs) contained in the EMA Guideline on setting health based exposure limits for use in risk identification in the manufacture of different medicinal products in shared facilities (EMA/CHMP/CVMP/SWP/169430/2012), and to obtain the following information:
To order an OEL monograph for this compound, just click the ADD TO CART button.
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Affygility Solutions’s OEL Fastrac service is an user-friendly system that enables us to make confident decisions and focus on moving the compound safely through our facility. We can quickly access the database to determine if a new drug is within the OEL Fastrac library, and if so, immediately download a detailed OEL banding report. The OEL Fastrac system has been a helpful tool in our overall EH&S program.